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KMID : 0390220150260010058
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Journal of Clinical Otolaryngology, Head and Neck Surgery
2015 Volume.26 No. 1 p.58 ~ p.63
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Office Based Consultation for the Globus Patients Who Having Throat Clearing
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Chang Dong-Sik
Park No-Seon
Cha Wang-Woon
Choi Myung-Su
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Abstract
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Background and Objectives：Recently, an extraesophageal reflux has been known as leading cause of the globus pharyngeus, maximal acid suppression therapy has been the center of the treatment. However, there are diverse potential causes causing globus symptom, some patients may not be beneficial of the acid suppression therapy. We aimed this study to evaluate the effect of office-based consultation to avoid throat clearing that can commonly encounter in globus patients.
Subjects and Methods：From October 2013 to August 2014, 70 globus patients having throat clearing were enrolled. Patients were randomly assigned to 2 groups prospectively. The treatment outcomes were compared between control and experimental groups after 8 weeks (control group was treated with only proton pump inhibitor (PPI), experimental group was treated with PPI combined consultation to avoid throat clearing).
Results：The change of the reflux symptom index (RSI) after treatment is calculated as [(initial RSI ? final RSI)/initial RSI ×100 (%)]. And, the grade of improvement is classified 4 levels (1=aggravated or improved less than 25%, 2=improved from 25 to 50%, 3=improved from 50 to 75%, 4=improved more than 75%). As compared with the grade of improvement between groups, the experimental group scored much high grade of improvement than control (p=0.008).
Conclusions：The office-based consultation for avoiding throat clearing in the globus patients can be beneficial to the patients in addition to acid suppression therapy.
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KEYWORD
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Laryngopharyngeal reflux, Globus
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